| 发明名称 |
INTERMEDIATES FOR THE PREPARATION OF ANALOGS OF HALICHONDRIN B |
| 摘要 |
Intermediates and methods of their use in the synthesis of analogs of halichondrin B are provided. |
| 申请公布号 |
US2015232490(A1) |
申请公布日期 |
2015.08.20 |
| 申请号 |
US201514624171 |
申请日期 |
2015.02.17 |
| 申请人 |
Eisai R&D Management Co., Ltd. |
发明人 |
Benayoud Farid;Calkins Trevor Lee;Chase Charles E.;Christ William |
| 分类号 |
C07F7/18;C07D307/28;C07C33/42 |
主分类号 |
C07F7/18 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A compound of formula F-2d: wherein: R′ is —CH═CH2 or —C(O)H; Alk is a C1-4 straight or branched aliphatic group; and PG5 is a suitable hydroxyl protecting group. |
| 地址 |
Tokyo JP |
