| 发明名称 | Anhydrous lenalidomide form-I | ||
| 摘要 | Anhydrous polymorphic form-I of anti cancer drug, Lenalidomide whose chemical name is 3-(4-amino-1-oxo-1,3-dihydro-isoindole-2-yl)-piperidine-2,6-dione, is disclosed. Alternate methods for making anhydrous polymorphic form-I of Lenalidomide are also disclosed. | ||
| 申请公布号 | US9108945(B2) | 申请公布日期 | 2015.08.18 |
| 申请号 | US201414151519 | 申请日期 | 2014.01.09 |
| 申请人 | Natco Pharma Limited | 发明人 | Konakanchi Durga Prasad;Gongalla Buchappa;Sikha Kotayya Babu;Kandaswamy Chandrasekar;Adibhatla Kali Satya Bhujanga Rao;Nannapaneni Venkaiah Chowdary |
| 分类号 | C07D401/00;A61K31/445;C07D401/04 | 主分类号 | C07D401/00 |
| 代理机构 | Kilpatrick Townsend & Stockton LLC | 代理人 | Kilpatrick Townsend & Stockton LLC |
| 主权项 | 1. An anhydrous unsolvated crystalline form of lenalidomide (Form-I) having weight loss of up to 0.13% between 25 and 225° C. by thermogravimetric analysis and characterized by its Powder XRD in accordance with FIG. 1a. | ||
| 地址 | Banjara Hills, Hyderabad IN | ||