代理机构 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
代理人 |
Rothwell, Figg, Ernst & Manbeck, P.C. |
主权项 |
1. A compound represented by Formula (I) or a salt thereof, wherein R1 is the same or different, and each represents C1-C6 alkyl; X1 and X2 independently represent N or CH; Y is a group represented by Formula (A) wherein the divalent moiety represented by is a nitrogen-containing C3-C10 heterocycloalkylene group, a group represented by Formula (B) wherein the divalent moiety represented by is a C3-C10 cycloalkylene group, or a group represented by Formula (C) wherein the divalent moiety represented by is a C6-C12 arylene group and wherein the methylene group of Subformulas (A), (B) and (C) is connected to the nitrogen of the bicycle; R2 is hydrogen, C2-C6 alkynyl, —C(═O)ORx, —C(═O)N(Rx)(Ry), hydroxy-C1-C6 alkyl, di(C1-C6 alkyl)amino-C1-C6 alkyl, or C2-C9 heteroaryl optionally having R3; and R3 is C1-C6 alkyl or di(C1-C6 alkyl)amino-C1-C6 alkyl; Z is —C(R4)═C(R5)(R6) or —C≡C—R7; R4, R5, and R6 are the same or different, and each represents hydrogen, halogen, C1-C6 alkyl optionally having R8, or a group represented by Formula (D) wherein the monovalent moiety represented by is a nitrogen-containing C3-C10 heterocycloalkyl group, R7 is hydrogen, C1-C6 alkyl, or hydroxy-C1-C6 alkyl; R8 is —ORx or —N(Rx)(Ry); R9 is C1-C6 alkyl, halogen, or —ORx; Rx and Ry are the same or different, and each represents hydrogen, C1-C6 alkyl, C3-C10 cycloalkyl, di(C1-C6 alkyl)amino-C1-C6 alkyl, or C1-C6 alkoxy-C1-C6 alkyl; l is an integer of 0 to 3; m is an integer of 1 to 3; and n is an integer of 0 to 2. |