CLINICAL TRIAL RECRUITMENT PLATFORM DRIVEN BY MOLECULAR PROFILE

摘要

Disclosed are platforms, systems, media, and methods for enabling a clinical trial administrator to identify individuals potentially eligible for a clinical trial based at least in part on an individual molecular phenotype, review profiles of identified individuals, and make clinical trial enrollment offers to identified individuals. Also disclosed are platforms, systems, media, and methods for enabling a patient to review and accept or decline clinical trial enrollment offers and identify relevant individuals, clinical trials, and therapies based at least in part on an individual molecular phenotype.

主权项

1. A computer-implemented suite of electronic interfaces for use by patients and clinical trial administrators on an electronic molecular-phenotype driven, clinical trial recruitment platform comprising: a digital processing device comprising an operating system configured to perform executable instructions and a memory device; and a computer program including instructions executable by the digital processing device to create an application comprising:
a. a software module configured to present an interface for allowing an individual to post a profile to a secure online marketplace for a defined duration, for the purpose of being recruited to clinical trials; b. a database of profiles, each profile comprising:
i. personal information, the personal information configured by the individual; andii. a molecular phenotype for the individual, the molecular phenotype determined by medical diagnostic testing performed at a qualified facility; c. a software module configured to execute automated direct transfer, on demand by the individual or their authorized healthcare representative, of molecular profiling diagnostic test results from a first storage at the qualified facility to a second storage accessible by the application; d. a software module configured to present an interface for allowing a clinical trial administrator to establish a search for the purpose of identifying individuals eligible for enrollment by entering clinical trial patient inclusion and exclusion criteria comprising a molecular phenotype; e. a software module configured to present an interface for allowing the clinical trial administrator to identify individuals eligible for the clinical trial, from among active posted profiles, based on comparison of the individual-posted profiles and the criteria; f. a software module configured to present an interface for allowing the clinical trial administrator to receive notifications when new individuals post a profile to the online marketplace and review profile information for identified individuals; g. a software module configured to present an interface for allowing a clinical trial administrator to make clinical trial enrollment offers to identified individuals, the enrollment offers comprising an invitation or presentation of opportunity to enroll in the clinical trial; h. a software module configured to present offers made to an individual or their authorized healthcare representative, the individual the subject of the offers; i. a software module configured to present an interface for allowing the individual or the authorized healthcare representative to select an offer from among the presented offers; and j. a software module configured to present an interface for allowing the clinical trial administrator to monitor clinical trial enrollment information, the clinical trial enrollment information comprising: status of open offers of enrollment and individuals available for enrollment in the clinical trial.