发明名称 TARGETED TGF.BETA. INHIBITION
摘要 This invention relates generally to bifunctional molecules including (a) a TGFßRII or fragment thereof capable of binding TGFß and (b) an antibody, or antigen binding fragment thereof, that binds to an immune checkpoint protein, such as Programmed Death Ligand 1 (PD-L1), uses of such molecules (e.g., for treating cancer), and methods of making such molecules.
申请公布号 CA2934979(A1) 申请公布日期 2015.08.13
申请号 CA20152934979 申请日期 2015.02.10
申请人 MERCK PATENT GMBH 发明人 LO, KIN-MING
分类号 C07K14/435;C07K14/71;C07K16/22;C07K16/28;C07K16/46;C07K19/00 主分类号 C07K14/435
代理机构 代理人
主权项
地址
您可能感兴趣的专利