| 发明名称 |
NRIP AS A BIOMARKER OF ABNORMAL FUNCTION OF MOTOR NEURONS |
| 摘要 |
The present invention provides a method for evaluating physiological state of motor neurons in a subject. The method comprises detecting an expression level of a nuclear receptor interaction protein (NRIP) in a biological sample from the subject; and comparing the expression level of the NRIP to a control value for NRIP; wherein detecting a decrease of the expression level of the NRIP in the biological sample from the subject as compared to the control value for NRIP indicates an abnormal function of the motor neurons of the subject |
| 申请公布号 |
US2015226750(A1) |
申请公布日期 |
2015.08.13 |
| 申请号 |
US201414178245 |
申请日期 |
2014.02.11 |
| 申请人 |
NATIONAL TAIWAN UNIVERSITY |
发明人 |
Chen Show-Li;Chen Hsin-Hsiung;Huang Yuan-Chun |
| 分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for evaluating a physiological state of motor neurons in a subject, comprising the following steps:
(1) detecting an expression level of a nuclear receptor interaction protein (NRIP) in a biological sample from the subject; and (2) comparing the expression level of the NRIP to a control value for NRIP; wherein detecting a decrease of the expression level of the NRIP in the biological sample from the subject as compared to the control value for NRIP indicates an abnormal function of the motor neurons of the subject. |
| 地址 |
Taipei TW |
