发明名称 |
METHOD AND DEVICES FOR X-RAY CRYSTALLOGRAPHY, IN PARTICULAR WITH MICROCRYSTALS OF BIOLOGICAL MACROMOLECULES |
摘要 |
A method of X-ray crystallography for investigating microscopic crystals, in particular microscopic crystals of biological macromolecules, comprises the steps of extruding a sample stream (1) with an injector nozzle device (100), wherein the sample stream (1) comprises a viscous liquid with microscopic crystals embedded therein, providing an X-ray beam (2) with a synchrotron source device (210) and irradiating the sample stream (1) with the X-ray beam (2), and collecting diffraction image data created by diffraction of the X-ray beam (2) by the microscopic crystals with a series of X-ray exposures of the sample stream (1). Furthermore, an injector nozzle device (100) and an X-ray crystallography apparatus (200) for X-ray crystallography investigations of microscopic crystals are described. |
申请公布号 |
WO2015117748(A1) |
申请公布日期 |
2015.08.13 |
申请号 |
WO2015EP00208 |
申请日期 |
2015.02.03 |
申请人 |
MAX-PLANCK-GESELLSCHAFT ZUR FÖRDERUNG DER WISSENSCHAFTEN E.V.;ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALFOF ARIZONA STATE UNIVERSITY |
发明人 |
DOAK, ROBERT BRUCE;SHOEMAN, ROBERT;BOTHA, SABINE;SCHLICHTING, ILME;BARENDS, THOMAS R.M.;NASS, KAROL |
分类号 |
G01N23/20 |
主分类号 |
G01N23/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|