发明名称 Method, apparatus and kit for the treatment of neurodegenerative diseases and impairments
摘要 A method, apparatus and kit have been discovered which regenerate with the use of odorants the connections of the neurons of the brain and central nervous system in the treatment of such person afflicted neuro-disorders caused by disease or trauma.
申请公布号 US9101652(B2) 申请公布日期 2015.08.11
申请号 US201313793592 申请日期 2013.03.11
申请人 Howard University 发明人 Nwulia Evaristus A.
分类号 A01N65/00;A61K36/752;A61K36/54;A61K36/53;A61K9/00;A61M16/00;A61M16/12;A61K36/00;A61M16/06;A61M21/00 主分类号 A01N65/00
代理机构 Fitch, Even, Tabin & Flannery, LLP 代理人 Fitch, Even, Tabin & Flannery, LLP
主权项 1. A method for treating a human suffering from symptoms of dementia, the method comprising: intranasally administering to said human suffering from symptoms of dementia a blend of odorants dispersed in a pharmaceutically acceptable oil, wherein said blend of odorants are two or more odorants selected from the group consisting of citrus extract, rosemary extract, cinnamon extract, banana oil, cumin extract, vanillin extract, ethylvanillin extract, garlic extract, paprika extract, curry extract, nutmeg extract, thyme extract, tarragon extract, celery extract, ginger extract, lavender extract, marjoram extract, basil leaf extract, cardamom extract, clove extract, chocolate extract and anise extract, each of the blend of odorants dispersed in a pharmaceutically acceptable oil being present at an amount of about 0.5 wt. % to about 6 wt. %, the administering including pumping the blend of odorants as a part of a flow of gas which includes oxygen and the odorant blend, the flow created by a pump which creates a positive pressure to create a flow of oxygen and the odorant blend through the nose of the human at a rate of about 0.5 to about 2 liters per minute at 25° C., the concentration of the blend of odorants and the time of treatment of the human being therapeutically effective for an improvement of a neurofunction of the human afflicted with the symptoms of dementia by at least 50% in short-term verbal memory of the human suffering from symptoms of dementia, the improvement being measured by a California Verbal Learning Test, Adult, Version 2.
地址 Washington DC US