发明名称 |
Coating formulations for scoring or cutting balloon catheters |
摘要 |
The present invention is related to scoring or cutting balloon catheters carrying at least on a portion of their surface at least one oxidation-insensitive drug or oxidation-insensitive polymer-free drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein the at least one oxidation-insensitive drug is selected of taxanes, thalidomide, statins, corticoids and lipophilic derivatives of corticoids, and the at least one lipophilic antioxidant is selected of nordihydroguaiaretic acid, resveratrol and propyl gallate. |
申请公布号 |
US9101684(B2) |
申请公布日期 |
2015.08.11 |
申请号 |
US201313975228 |
申请日期 |
2013.08.23 |
申请人 |
ANGIOSCORE, INC. |
发明人 |
Speck Ulrich;Berg Madeleine Caroline |
分类号 |
A61F2/00;A61L29/08;A61L29/16;A61L31/16;A61M25/10 |
主分类号 |
A61F2/00 |
代理机构 |
Faegre Baker Daniels LLP |
代理人 |
Faegre Baker Daniels LLP |
主权项 |
1. A scoring or cutting angioplasty balloon catheter carrying at least on a portion of its surface a therapeutically effective amount of the oxidation-insensitive drug paclitaxel; an amount of the lipophilic antioxidant resveratrol that will protect the paclitaxel from premature loss during delivery to an angioplasty site and that is 3-100% by weight of the paclitaxel; and an amount of polymer that is 0-20% by weight of the paclitaxel. |
地址 |
Colorado Springs CO US |