发明名称 DISEASE PROGRESSION PARAMETERS AND USES THEREOF FOR EVALUATING MULTIPLE SCLEROSIS
摘要 Methods, systems and kits to detect and/or quantify disease progression in a subject having a progressive form of MS are disclosed.
申请公布号 US2015220693(A1) 申请公布日期 2015.08.06
申请号 US201314421561 申请日期 2013.08.08
申请人 BIOGEN IDEC MA INC. 发明人 Cadavid Diego;Kinch Deborah Ann;Lee Sophia;Xu Lei
分类号 G06F19/00 主分类号 G06F19/00
代理机构 代理人
主权项 1. A method of treating or preventing a progressive form of multiple sclerosis (MS) in a subject, comprising: acquiring a value of disease progression that comprises a measure of one or more of: upper extremity function, lower extremity function, and/or a measure of ambulatory function other than the Expanded Disability Status Scale (EDSS)), and responsive to a determination of the value of disease progression, performing one, two, three, four or more of: identifying the subject as a progressor or non-progressor of the disability; administering an MS therapy; selecting or altering a dosing of an MS therapy; selecting or altering the schedule or time course of an MS therapy; or selecting an alternative MS therapy, thereby treating or preventing MS in the subject.
地址 Cambridge MA US