主权项 |
1. A method of treating or preventing a progressive form of multiple sclerosis (MS) in a subject, comprising:
acquiring a value of disease progression that comprises a measure of one or more of: upper extremity function, lower extremity function, and/or a measure of ambulatory function other than the Expanded Disability Status Scale (EDSS)), and responsive to a determination of the value of disease progression, performing one, two, three, four or more of: identifying the subject as a progressor or non-progressor of the disability; administering an MS therapy; selecting or altering a dosing of an MS therapy; selecting or altering the schedule or time course of an MS therapy; or selecting an alternative MS therapy, thereby treating or preventing MS in the subject. |