MULTISPECTRAL WIDE-FIELD ENDOSCOPIC IMAGING OF FLUORESCENCE

摘要

Improved methods, systems and apparatus relating to wide field fluorescence and reflectance imaging are provided, including improved methods, systems and apparatus relating to removal of background signals such as autofluorescence and/or fluorophore emission cross-talk; distance compensation of fluorescent signals; and co-registration of multiple signals emitted from three dimensional tissues.

主权项

1. A wide field spectral imaging apparatus, comprising:
a wide field spectral imager configured to concurrently image an object at a varying depth from the imager; a processor coupled to the wide field spectral imager, the processor comprising instructions to decrease a background fluorescence signal and enhance a fluorescence signal of interest.