| 发明名称 |
TACI AS AN ANTI-TUMOR AGENT |
| 摘要 |
A method of treating a mammal for a condition associated with undesired cell proliferation comprising administering to said mammal an effective amount of a TACI reagent, wherein said reagent extends mean survival time of said mammal by about 10% or more as compared to the absence of administering the TACI reagent. |
| 申请公布号 |
US2015218247(A1) |
申请公布日期 |
2015.08.06 |
| 申请号 |
US201514631217 |
申请日期 |
2015.02.25 |
| 申请人 |
BIOGEN IDEC MA INC. ;TOPOTARGET SWITZERLAND SA |
发明人 |
Ambrose Christine;Thompson Jeffrey;Rennert Paul;Schneider Pascal |
| 分类号 |
C07K14/705 |
主分类号 |
C07K14/705 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of reducing the size of a tumor located on or in a mammal comprising administering a polypeptide to the mammal having the tumor, wherein the polypeptide comprises a sequence that specifically binds to APRIL and shares at least 95% sequence identity with SEQ ID NO:1, and wherein administering the polypeptide reduces the size of the tumor. |
| 地址 |
Cambridge MA US |
