METHODS TO CAPTURE AND/OR REMOVE HIGHLY ABUNDANT RNAS FROM A HETEROGENOUS RNA SAMPLE

摘要

The invention is directed to a method of using DNA oligonucleotides as baits to capture and selectively remove highly abundant RNAs from a heterogeneous RNA sample for improved enrichment of other RNAs that are unrelated to the highly abundant RNAs.

主权项

1. A method of selectively removing a undesired RNA target from a population of RNA molecules, comprising:
(a) contacting the population of RNA molecules with a DNA oligonucleotide comprising a bait to form a mixture; and (b) isolating the undesired RNA target from the mixture.