Uso combinado de 25-hidroxivitamina d3 e vitamina d3 para melhorar a densidade mineral do osso e para tratar a osteoporose

摘要

We disclose the combined use of vitamin D (cholecalciferol) and 25-OH D3 (calcifediol) to treat and/or prevent osteoporosis. One or more bisphosphonate compounds to inhibit bone resorption may also be used. Forms and dosages of a pharmaceutical composition, as well as processes for manufacturing medicaments, are also disclosed.