| 摘要 |
<p>The invention deals with a composition for treating iron overload in patients with β-thalassemia and particularly deals with a combination of iron chelators comprising of hydroxyurea, deferasirox and deferiprone. The combination of hydroxyurea, deferasirox and deferiprone provides excellent results when used in a ratio of 1:1:4 of the respective drugs. On comparing the dry weight of iron levels/gm of liver and heart tissues in different groups of mice against that which were not treated with any drug, it was observed that the mean dry weight of liver iron showed a significant reduction in the combination group.</p> |
