| 摘要 |
<p>Disclosed herein is a compound of formula (II), wherein the variables are defined in the specification, or an enantiomer, a mixture of enantiomers, a mixture of two or more diastereomers, a tautomer, or a mixture of two or more tautomers thereof; or a pharmaceutically acceptable salt, solvate, hydrate, or prodrug thereof; and the use thereof in the treatment of CCR3-mediated, eosinophil-related, basophil-related or mast cell-related disorder, disease or condition, such as asthma, exercise induced asthma, allergic rhinitis, atopic dermatitis, chronic obstructive pulmonary disease, or allergic conjunctivitis. Compounds of the disclosure include: 4-(2,5-dimethylphenoxy)-3-(piperazin-1-ylsulfonyl)benzonitrile</p> |
