DIHYDROCHALCONE DERIVATIVES AND THEIR USE AS ANTIBIOTIC AGENTS

摘要

A compound of formula (I) as well as pharmaceutical compositions comprising same is provided. An extract of a plant belonging to a species of Populus, the extract comprising this compound is also provided. These can be used as antibacterial for treating bacterial infection.;

主权项

1. A compound of formula (I): wherein: one of A and B is H and the other is G is R2 and E isor
G and E are both carbon atoms, said carbon atoms being linked together by a single bond, G being substituted byand E being substituted by R6;
each of R1, R2, R3, and R4 independently being H or alkyl; and each of R5 and R6, independently being H, OH, alkyl, or alkoxy, or a salt, ester, or solvate thereof.