发明名称 |
AGENTS FOR TREATING GENETIC DISEASES RESULTING FROM NONSENSE MUTATIONS, AND METHODS FOR IDENTIFYING THE SAME |
摘要 |
Disclosed is treatment of genetic neurodegenerative or neurodevelopmental diseases that are caused by or associated with nonsense mutations or premature termination codons using macrolides. Further disclosed are methods for identifying agents that induce read-through of nonsense mutations and premature termination codons and uses thereof. |
申请公布号 |
SG11201504933W(A) |
申请公布日期 |
2015.07.30 |
申请号 |
SG11201504933W |
申请日期 |
2013.12.24 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD. |
发明人 |
ROSIN-ARBESFELD, RINA;CASPI, MICHAL;MEGIDDO, DALIA |
分类号 |
A61K31/7048;A61P25/00;A61P25/28;A61P31/00 |
主分类号 |
A61K31/7048 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|