| 摘要 |
<p>An inhaler (2) is for use with a pharmaceutical capsule (36) containing an active pharmaceutical ingredient (API) and a carrier powder. The inhaler (2) comprises a capsule opener, a capsule chamber (12) for retaining an opened capsule (36), and a deagglomeration chamber (16) for detaching at least a portion of the API from the carrier powder. When a user inhales through an inhaler outlet downstream of the deagglomeration chamber, air enters the capsule chamber (12) through an air inlet (24), flows from the capsule chamber (12) into the deagglomeration chamber (16), and out of the outlet. The user's inhalation generates air pressures Piat the outlet, Pint between the capsule chamber (12) and the deagglomeration chamber (16) and Po at the outlet. The inhaler (2) is designed such that (Pint-Po)/(Pi- Po)>0.33.</p> |
