发明名称 A METHOD FOR PROGNOSIS OF GLOBAL SURVIVAL AND SURVIVAL WITHOUT RELAPSE IN HEPATOCELLULAR CARCINOMA
摘要 The present invention relates to the technical field of hepatocellular carcinoma (HCC) management, and more precisely to the prognosis of HCC aggressiveness and associated therapeutic decisions. The invention provides a new prognosis method of HCC aggressiveness, based on determination in vitro and analysis of an expression profile comprising genes TAF9, RAMP3, HN1, KRT19, and RAN. The invention also provides kits for the prognosis of HCC aggressiveness, and methods of treatment of HCC in a subject based on a preliminary prognosis of said subject HCC aggressiveness.
申请公布号 EP2898094(A1) 申请公布日期 2015.07.29
申请号 EP20130766953 申请日期 2013.09.23
申请人 INTEGRAGEN;INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE (INSERM);UNIVERSITÉ PARIS DESCARTES 发明人 DE REYNIES, AURÉLIEN;LAURENT-PUIG, PIERRE;ZUCMAN-ROSSI, JESSICA;NAULT, JEAN-CHARLES
分类号 C12Q1/68 主分类号 C12Q1/68
代理机构 代理人
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