| 发明名称 | Bile acid derivatives as FXR ligands for the prevention or treatment of FXR-mediated diseases or conditions | ||
| 摘要 | The present invention relates to compounds of formula (I):;wherein R is hydrogen or alpha-hydroxy,the hydroxyl group in position 7 is in the alpha or beta position;and pharmaceutically acceptable salts, solvates or amino acid conjugates thereof. | ||
| 申请公布号 | US9090652(B2) | 申请公布日期 | 2015.07.28 |
| 申请号 | US201314012401 | 申请日期 | 2013.08.28 |
| 申请人 | INTERCEPT PHARMACEUTICALS, INC. | 发明人 | Pellicciari Roberto;Fiorucci Stefano;Pruzanski Mark |
| 分类号 | A61K31/575;C07J9/00;C07J31/00 | 主分类号 | A61K31/575 |
| 代理机构 | Cooley, LLP | 代理人 | Cooley, LLP |
| 主权项 | 1. A compound selected from | ||
| 地址 | New York NY US | ||