| 发明名称 |
Aromatic bycyclic derivatives as CXCR4 receptor modulators |
| 摘要 |
The present invention relates to novel aromatic bicyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals as modulators of the CXCR4 receptor. |
| 申请公布号 |
US9090624(B2) |
申请公布日期 |
2015.07.28 |
| 申请号 |
US201213565478 |
申请日期 |
2012.08.02 |
| 申请人 |
Allergan, Inc. |
发明人 |
Vuligonda Vidyasagar;Beard Richard L.;Vu Thong;Donello John E.;Rodrigues Gerard;Viswanath Veena;Garst Michael E. |
| 分类号 |
C07D495/04;A61K31/517;A61K31/519;C07D401/12 |
主分类号 |
C07D495/04 |
| 代理机构 |
|
代理人 |
Bass Jonathan Y. |
| 主权项 |
1. A compound represented by Formula I, its enantiomers, diastereoisomers, tautomers or a pharmaceutically acceptable salt thereof, wherein: “” is abond;
n is 1; m is 1; R1 is S; R2 is N; R3 is N; R4 is H; R5 is R6 is H; and R7 is substituted or unsubstituted C1-6 alkyl, or substituted or unsubstituted benzyl. |
| 地址 |
Irvine CA US |
