| 发明名称 | Pyrazolone derivatives as PDE4 inhibitors | ||
| 摘要 | The compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione is a novel effective inhibitor of the type 4 phosphodiesterase useful in the treatment of psoriasis or atopic dermatitis. | ||
| 申请公布号 | US9090597(B2) | 申请公布日期 | 2015.07.28 |
| 申请号 | US201414473338 | 申请日期 | 2014.08.29 |
| 申请人 | Takeda GmbH | 发明人 | Schmidt Beate;Scheufler Christian;Volz Jürgen;Feth Martin;Hummel Rolf-Peter;Hatzelmann Armin;Zitt Christof;Wohlsen Andrea;Marx Degenhard;Kley Hans-Peter;Ockert Deborah;Heuser Anke;Christiaans Johannes A. M.;Sterk Geert Jan;Menge Wiro M. P. B. |
| 分类号 | C07D401/14;A61K31/4152 | 主分类号 | C07D401/14 |
| 代理机构 | Nath, Goldberg & Meyer | 代理人 | Nath, Goldberg & Meyer ;Goldberg Joshua B. |
| 主权项 | 1. A method for treating psoriasis or atopic dermatitis in a patient comprising administering to a patient in need thereof the compound 1-(2-{4-[3-(3,4-dimethoxyphenyl)-4,4-dimethyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]piperidin-1-yl}-2-oxoethyl)pyrrolidine-2,5-dione. | ||
| 地址 | Constance DE | ||