Device for adaptive processing of an endocardial acceleration signal

摘要

A device, for adaptive processing of an endocardial acceleration signal, continuously collects an endocardial acceleration EA signal and divides it into EA sub-signals, each over the duration of one cardiac cycle. The EA sub-signals are separated into the EA1 and EA2 components. A cross-correlation between the EA sub-signals of each component and a time calibration compared to a reference cycle, and a series of validation criteria is applied. The result is an average overall EA signal for a cycle. A change in the patient's condition or an occurrence of a predetermined event in the patient is detected (24) and, as a result there is dynamic adaptation of at least one of said validation criteria and/or at least one of the preprocessing parameters for calculating the EA signal average.

主权项

1. An implantable medical device, comprising:
a microprocessor; an endocardial acceleration sensor; and a non-transitory machine-readable storage medium having instructions stored thereon that, when executed by the microprocessor, cause the microprocessor to:
collect an endocardial acceleration (EA) signal over a plurality of cardiac cycles using the endocardial acceleration sensor;divide the collected EA signal into a plurality of EA sub-signals, wherein each of the plurality of EA sub-signals corresponds to a single cardiac cycle of the plurality of cardiac cycles;isolate at least one signal component in each of the plurality of EA sub-signals, wherein the at least one signal component is associated with a type of heart sound;select a subset of EA sub-signals from among the plurality of EA sub-signals based on the at least one signal component of the EA sub-signals and one or more validation criteria;generate a combined EA sub-signal based upon the selected subset of EA sub-signals;detect at least one of a change in a condition of a patient and an occurrence of a predetermined event in the patient; andmodify at least one of the one or more validation criteria in response to detecting the at least one of the change in the condition of the patient and the occurrence of the predetermined event.