| 主权项 |
1. A compound having formula A-I: or a salt thereof; wherein:
G1 is hydrogen, R′, C(O)R′, C(S)R′, S(O)R′, S(O)2R′, Si(CH3)2R′, P(O)(OR′)3, P(S)(OR′)3, or B(OR′)2;G2 is halo, CN, CF3, isopropyl, or phenyl wherein said isopropyl or phenyl is optionally substituted with up to 3 substituents independently selected from WRW;G3 is an isopropyl or a C3-C10 cycloaliphatic ring, wherein said G3 is optionally substituted with up to 3 substituents independently selected from WRW;provided that when G1 is methyl, G3 is tert-butyl, then G2 is not 2-amino-4-methoxy-5-tert-butyl-phenyl;W is a bond or is an optionally substituted C1-C6 alkylidene chain, wherein up to two methylene units of W are optionally and independently replaced by —CO—, —CS—, —COCO—, —CONR′—, —CONR′NR′—, —CO2—, —OCO—, —NR′CO2—, —O—, —NR′CONR′—, —OCONR′—, —NR′NR′, —NR′NR′CO—, —NR′CO—, —S—, —SO, —SO2—, —NR′—, —SO2NR′—, NR′SO2—, or —NR′SO2NR′—;RW is independently R′, halo, NO2, CN, CF3, or OCF3; andR′ is independently selected from hydrogen or an optionally substituted group selected from a C1-C8 aliphatic group, a 3-8-membered saturated, partially unsaturated, or fully unsaturated monocyclic ring having 0-3 heteroatoms independently selected from nitrogen, oxygen, or sulfur, or an 8-12 membered saturated, partially unsaturated, or fully unsaturated bicyclic ring system having 0-5 heteroatoms independently selected from nitrogen, oxygen, or sulfur; or two occurrences of R′ are taken together with the atom(s) to which they are bound to form an optionally substituted 3-12 membered saturated, partially unsaturated, or fully unsaturated monocyclic or bicyclic ring having 0-4 heteroatoms independently selected from nitrogen, oxygen, or sulfur. |
