发明名称 |
Method of inhibiting bile acid absorption by administering an agonist of a guanylate cyclase receptor |
摘要 |
This invention also provides a method to prevent, control, and treat a lipid metabolism disorder, a biliary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases. |
申请公布号 |
US9089612(B2) |
申请公布日期 |
2015.07.28 |
申请号 |
US201013513224 |
申请日期 |
2010.12.03 |
申请人 |
SYNERGY PHARMACEUTICALS, INC. |
发明人 |
Shailubhai Kunwar |
分类号 |
A61K38/10;C07K7/08;A61K47/48;A61P1/04 |
主分类号 |
A61K38/10 |
代理机构 |
|
代理人 |
Kozakiewicz Cynthia;Elrifi Ivor |
主权项 |
1. A method for inhibiting bile acid absorption, comprising administering to a patient in need thereof, an effective dosage of a guanylate cyclase receptor agonist having the sequence of SEQ ID NO:104. |
地址 |
New York NY US |