发明名称 Method of inhibiting bile acid absorption by administering an agonist of a guanylate cyclase receptor
摘要 This invention also provides a method to prevent, control, and treat a lipid metabolism disorder, a biliary disorder, cardiovascular disease, obesity or an endocrine disorder by administering at least one agonist of guanalyte cyclase receptor either alone or in combination with a compound typically used to treat the disorder and or with an inhibitor of cGMP-dependent phosphodieasterases.
申请公布号 US9089612(B2) 申请公布日期 2015.07.28
申请号 US201013513224 申请日期 2010.12.03
申请人 SYNERGY PHARMACEUTICALS, INC. 发明人 Shailubhai Kunwar
分类号 A61K38/10;C07K7/08;A61K47/48;A61P1/04 主分类号 A61K38/10
代理机构 代理人 Kozakiewicz Cynthia;Elrifi Ivor
主权项 1. A method for inhibiting bile acid absorption, comprising administering to a patient in need thereof, an effective dosage of a guanylate cyclase receptor agonist having the sequence of SEQ ID NO:104.
地址 New York NY US