发明名称 MODULATION OF AXON DEGENERATION
摘要 PROBLEM TO BE SOLVED: To provide treatment of neurological disorders and nervous system injuries, and methods for inhibiting degeneration of neurons or portions thereof.SOLUTION: A method comprises administering to a neuron or a portion thereof an agent that modulates: (i) the activity or expression of a target protein in the neuron or portion thereof, or (ii) a process in the neuron or portion thereof. The agent is selected from among an antibody, a polypeptide, a peptide, a peptibody, a nucleic acid molecule, a short interfering RNA (siRNA), a polynucleotide, an aptamer, a small molecule, and a polysaccharide.
申请公布号 JP2015134781(A) 申请公布日期 2015.07.27
申请号 JP20150023102 申请日期 2015.02.09
申请人 GENENTECH INC 发明人 RYAN WATTS;MARK CHEN;JOSEPH WESLEY LEWCOCK;CHRISTINE POZNIAK;ARUNDHATI SENGUPTA-GHOSH
分类号 A61K45/00;A61K31/517;A61K31/713;A61K38/00;A61K39/395;A61K48/00;A61P1/08;A61P1/16;A61P3/10;A61P13/12;A61P19/02;A61P21/02;A61P25/00;A61P25/04;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/20;A61P25/22;A61P25/24;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P31/18;A61P31/22;A61P35/00 主分类号 A61K45/00
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