发明名称 REMOVAL OF VIRULENCE FACTOR THROUGH EXTRACORPOREAL THERAPY
摘要 PROBLEM TO BE SOLVED: To provide a method for removing, from mammalian blood, pathogens or toxins derived from the pathogens selected from the group consisting of Bacillus anthracis, Pseudomonas aeruginosa, and Staphylococcus aureus.SOLUTION: The invention provides a method comprising the steps of: contacting a blood sample with a carbohydrate, such as a heparin, which has a binding affinity for a pathogen or toxin, and is immobilized on a solid substrate under conditions allowing the binding of the solid substrate to the pathogen or toxin in the blood sample; and separating the sample from the substrate, so that the pathogen or toxin is at least partially retained, or the substrate and the removed sample have a reduced amount of the pathogen or toxin.
申请公布号 JP2015131831(A) 申请公布日期 2015.07.23
申请号 JP20150044951 申请日期 2015.03.06
申请人 EXTHERA MEDICAL CORP 发明人 KEITH MCCREA;ROBERT S WARD
分类号 A61K35/14;A61M1/36;A61P7/00;A61P7/08;A61P31/00;A61P31/04;G01N30/88 主分类号 A61K35/14
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