| 发明名称 | Fatty acid conjugates of statin and FXR agonists; compositions and method of uses | ||
| 摘要 | The invention relates to fatty acid statin conjugates and fatty acid FXR agonist conjugates; compositions comprising an effective amount of a fatty acid statin conjugate or a fatty acid FXR agonist conjugate; and methods for treating or preventing a metabolic disease comprising the administration of an effective amount of a fatty acid statin conjugate or a fatty acid FXR agonist conjugate. | ||
| 申请公布号 | US9084826(B2) | 申请公布日期 | 2015.07.21 |
| 申请号 | US201313874993 | 申请日期 | 2013.05.01 |
| 申请人 | Catabasis Pharmaceuticals, Inc. | 发明人 | Milne Jill C.;Jirousek Michael R.;Ting Amal;Vu Chi B.;Wensley Allison |
| 分类号 | A61K31/58;A61K47/48;A61K31/505;A61K31/366;A61K31/40 | 主分类号 | A61K31/58 |
| 代理机构 | Goodwin Procter LLP | 代理人 | Goodwin Procter LLP |
| 主权项 | 1. A molecular conjugate comprising a statin selected from the group consisting of atorvastatin, cerivastatin, fluvastatin, lovastatin, mevastatin, pitavasatin, pravastatin, rosuvastatin, and simvastatin covalently linked to a fatty acid, wherein the fatty acid is selected from the group consisting of lipoic acid and omega-3 fatty acids. | ||
| 地址 | Cambridge MA US | ||