| 发明名称 | Compositions and methods for treating skin cancer associated diseases | ||
| 摘要 | The invention provides compositions and methods for treating skin cancer associated diseases. Specifically, the invention relates to topically administering a signaling pathway inhibitor or a related compound to treat pre-cancerous skin lesions, skin tumors, and their associated diseases or disorders. | ||
| 申请公布号 | US9084790(B2) | 申请公布日期 | 2015.07.21 |
| 申请号 | US201313786926 | 申请日期 | 2013.03.06 |
| 申请人 | The Trustees of the University of Pennsylvania | 发明人 | Seykora John T. |
| 分类号 | A01N43/42;A61K31/44;A61K31/519;A61K31/4745;A61K31/506;A61K31/277;A61K31/4184;A61K31/517;A61K45/06;A61K9/00;A61K47/10;A61K47/20 | 主分类号 | A01N43/42 |
| 代理机构 | Pearl Cohen Zedek Latzer Baratz LLP | 代理人 | Cohen Mark S.;Pearl Cohen Zedek Latzer Baratz LLP |
| 主权项 | 1. A method for treating a skin cancer related disease or disorder in a subject, the method comprising: topically administering to said subject a therapeutically effective amount of a PI3K/PDK1/AKT signaling pathway tyrosine kinase inhibitor, wherein the disease or disorder is actinic keratosis, a squamous cell carcinoma in situ like lesion, or a cutaneous squamous cell carcinoma. | ||
| 地址 | Philadelphia PA US | ||