| 发明名称 |
CRYSTALLINE POLYMORPHIC FORMS OF AN ANTIDIABETIC COMPOUND |
| 摘要 |
The present invention relates to polymorphic forms of a compound of formula A:;;This compound is useful as a glucagon receptor antagonist and serves as a pharmaceutically active ingredient for the treatment of type 2 diabetes and related conditions, such as hyperglycemia, obesity, dyslipidemia, and the metabolic syndrome. Hydrates, hemihydrates, anhydrates and similar polymorphic forms are included. |
| 申请公布号 |
US2015197490(A1) |
申请公布日期 |
2015.07.16 |
| 申请号 |
US201514669303 |
申请日期 |
2015.03.26 |
| 申请人 |
Merck Sharp & Dohme Corp. |
发明人 |
Chung John Y. L.;Zhang Yanfeng;Cote Aaron S.;Scott Jeremy;Vaynshteyn Yekaterina |
| 分类号 |
C07D209/18 |
主分类号 |
C07D209/18 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A crystalline polymorphic form of a compound of formula A: or a pharmaceutically acceptable salt thereof, selected from the group consisting of a free acid hydrate of polymorphic Form I and an anhydrous free acid of polymorphic Form I. |
| 地址 |
Rahway NJ US |
