发明名称 |
METHOD AND MEANS FOR DIAGNOSING AND TREATING ALLERGY |
摘要 |
Disclosed is a method for diagnosing allergy in a human or animal patient, wherein the level of species-specific lipocalin, especially lipocalin 2 in a human patient, is measured in a sample of said patient and wherein a lowered level of said lipocalin compared to the level of said lipocalin in the corresponding sample of a human or animal that has no allergy, is indicative of an allergy, as well as a kit for performing this method, and a kit for quality control of allergen molecules or extracts used for immunotherapy of allergy by determining its siderophore-iron ligand load and thus immunomodulatory potency. Further, lipocalin proteins for use in treatment or prevention of allergies are provided, preferably complexed with siderophore-iron ligands. |
申请公布号 |
WO2015104270(A1) |
申请公布日期 |
2015.07.16 |
申请号 |
WO2015EP50126 |
申请日期 |
2015.01.07 |
申请人 |
BIOMEDICAL INTERNATIONAL R+D GMBH |
发明人 |
ROTH-WALTER, FRANZISKA;JENSEN-JAROLIM, ERIKA;GOMEZ-CASADO, CRISTINA;DIAZ PERALES, ARACELI;FERNANDEZ PACIOS, LUIS;SINGER, JOSEF |
分类号 |
G01N33/68 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|