INTEGRATED SYSTEM FOR LIQUID SEPARATION AND ELECTROSPRAY IONIZATION

摘要

The present invention relates to an integrated system for liquid separation, such as LC, CE, affinity chromatography, and ion exchange chromatography. A preferred aspect relates to a specialised protection means for protecting the fragile electrospray needle when not in use. Another preferred aspect relates to a specialised electrical contact means for applying voltage to the electrospray needle. The invention comprises an integrated system for liquid separation and electrospray ionization comprising: a separation column; and an electrospray emitter connected with the separation column. In one aspect there is a retractable protective sleeve (8) for covering and supporting the electrospray emitter (2) along at least a portion of its axis. In another aspect there is an electrically conducting sheath surrounding the emitter and providing an electrical connection.

主权项

1. An integrated system for liquid separation and electrospray ionization comprising:
a separation column; an electrospray emitter connected with the separation column; and a retractable protective sleeve (8) for covering and/or supporting the electrospray emitter along at least a portion of its axis, said protective sleeve is slidably mounted around the electrospray emitter;wherein the retractable protective sleeve is moveable to an extended position wherein a tip of the electrospray emitter is covered by the protective sleeve, and wherein a resilient member is provided to bias the protective sleeve towards the extended position wherein it covers the tip of the electrospray emitter.