发明名称 METHOD FOR PRODUCING 1-SUBSTITUTED-3-FLUOROALKYLPYRAZOLE-4-CARBOXYLIC ACID ESTER
摘要 <p>The present invention is a method for producing a 1-substituted-3-fluoroalkylpyrazole-4-caroxylic acid ester, the method comprising a step of adding, to a first reaction liquid containing an alkyl hydrazine and a first organic solvent, a second reaction liquid containing an acyl acetic acid ester derivative and a second organic solvent in 0.5 to 30 hours to react the first reaction liquid with the second reaction liquid at a reaction temperature of -5 to 80°C under stirring in the absence of a base and an acid, wherein the first organic solvent and the second organic solvent are each at least any one of benzene, toluene, xylene, chlorobenzene, dichlorobenzene, ethyl acetate, butyl acetate, and dimethyl carbonate, a total mass of the first organic solvent and the second organic solvent is 1 to 60 times a mass of the acyl acetic acid ester derivative, and an amount of the first organic solvent in a total amount of the first organic solvent and the second organic solvent is 40 to 95% by mass.</p>
申请公布号 EP2894150(A1) 申请公布日期 2015.07.15
申请号 EP20130836036 申请日期 2013.03.14
申请人 TAMA KAGAKU KOGYO CO., LTD. 发明人 NOBESHIMA, HIROBUMI;KOYAMA, NAOKI;HARADA, MASAYUKI
分类号 C07D231/14 主分类号 C07D231/14
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