发明名称 METHOD OF TREATING EPSTEIN-BARR VIRAL INFECTION IN HIV-INFECTED CHILDREN
摘要 FIELD: medicine.SUBSTANCE: treating an active form of Epstein-Barr viral infection in the children with an inactive HIV infection involves conducting high-active antiretroviral therapy accompanying administering inosin pranobex prescribed orally from the first day of treatment in a daily dose of 50 mg/kg of body weight, 3-4 times a day to make three courses of 10 days each, as well as using suppositories of interferon alpha-2b + taurine per rectum according to the schedule: for the first 10 days of treatment - one suppository two times a day - in the morning and in the evening, every 12 hours; further - one suppository at the bedtime every second day for three months. The method enables reducing a rate and an intensity of the Epstein-Barr viral infection symptoms by reducing the lymphocyte, blood plasma, oropharyngeal mucus Epstein-Barr virus content and improving the immunological status presented by normalising CD3+ lymphocyte, CD4+ lymphocyte, CD95+ lymphocyte, annexin-V+ lymphocyte, annexin-V+/propidium+ lymphocyte, CD19+ lymphocyte counts.EFFECT: reducing the rate and intensity of symptoms.2 tbl, 2 ex
申请公布号 RU2555474(C1) 申请公布日期 2015.07.10
申请号 RU20140136626 申请日期 2014.09.09
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "ROSTOVSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GBOU VPO ROSTGMU MINZDRAVA ROSSII) 发明人 DENISENKO VALENTIN BORISOVICH;SIMOVAN'JAN EHMMA MKRTICHEVNA
分类号 A61K31/5375;A61K38/21;A61P31/22 主分类号 A61K31/5375
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