Combination of biomarkers for forecasting a response or non-response to an anti-HCV treatment

摘要

The application relates to means for forecasting whether an individual infected with one or more HCVs has a strong probability of responding to an anti-HCV treatment that will comprise the administration of interferon and of ribavirin, or whether, on the contrary, this individual has a strong probability of not responding to this anti-HCV treatment. The means of the invention implement in particular the assay of the expression levels of selected genes, said selected genes being: - at least one gene among MBL2, LGALS3BP and IL8, and - at least one gene among G1P2, CCL21 and CXCL10, and - optionally, at least one gene among AFP, CRP, CXCL11, CXCL6, CXCL9, FGF7, MDK, MMP2, SFN, TGFB2 and VEGFD.