发明名称 |
TOPICAL VITAMIN D AND UBIQUINOL ORAL SUPPLEMENT COMPOSITIONS |
摘要 |
A topical vitamin D and UBIQUINOL supplement composition useful in treating oral inflammation and reducing oxidative stress comprising: a supplement mixture of vitamin D and UBIQUINOL in an aqueous-free emulsion containing: spilanthes extract, stabilizing compositions for UBIQUINOL and trans-oral mucosal absorption facilitators for the supplement mixture; where the emulsion forms a mucoadhesive gel in the presence of saliva, that effects passive diffusion through the oral mucosa of the supplement mixture and spilanthes extract regulating: in vivo availability and immune response of the supplement mixture, and maintaining adequate levels of circulating vitamin D and of adjunctively administered UBIQUINOL, while minimizing the risk of hypercalcemia. |
申请公布号 |
EP2890385(A1) |
申请公布日期 |
2015.07.08 |
申请号 |
EP20130845305 |
申请日期 |
2013.10.10 |
申请人 |
PREMIER DENTAL PRODUCTS COMPANY |
发明人 |
MCHALE, WILLIAM, A.;BROWN, DALE, G. |
分类号 |
A61K31/59;A61K9/00;A61K31/05;A61K31/09;A61K31/592;A61K31/593;A61K36/28;A61K47/34;A61P1/02 |
主分类号 |
A61K31/59 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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