主权项 |
1. A human serum albumin (HSA) comprising a non-naturally encoded amino acid at one or more of the following positions: 34, 82, 172, 301, 364, and 505 of SEQ ID NO: 1, linked to one or more biologically active molecules selected from the group consisting of relaxin, angiotensin peptides, antibiotic peptides, antigenic polypeptides, anti-microbial peptides, apoptosis related peptides, atrial natriuretic peptides, bag cell peptides, bombesin peptides, bone GLA peptides, bradykinin peptides, brain natriuretic peptides, C-peptides, C-type natriuretic peptides, calcitonin peptides, calcitonin gene related peptides, CART peptides, casomorphin peptides, chemotactic peptides, cholecystokinin peptides, colony-stimulating factor peptides, corticortropin releasing factor peptides, cortistatin peptides, cytokine peptides, dermorphin peptides, dynorphin peptides, endorphin peptides, endothelin peptides, ETa receptor antagonist peptides, or ETb receptor antagonist peptides. |