| 发明名称 |
ANTAGONISTS OF ACTIVIN-ACTRIIA AND USES FOR INCREASING RED BLOOD CELL LEVELS |
| 摘要 |
In certain aspects, the present invention provides compositions and methods for increasing red blood cell and/or hemoglobin levels in vertebrates, including rodents and primates, and particularly in humans. |
| 申请公布号 |
US2015183845(A1) |
申请公布日期 |
2015.07.02 |
| 申请号 |
US201414549263 |
申请日期 |
2014.11.20 |
| 申请人 |
Acceleron Pharma, Inc. |
发明人 |
Sherman Matthew L.;Seehra Jasbir;Borgstein Niels |
| 分类号 |
C07K14/495;C07K16/00;A61K38/17;C07K16/22;A61K38/22 |
主分类号 |
C07K14/495 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A method for increasing red blood cell levels in a patient in need thereof, the method comprising administering to the patient an effective amount of an activin-ActRIIa antagonist at a dosing interval in a range of once per week to once every 90 days. |
| 地址 |
Cambridge MA US |
