PROCESS OF PRODUCING POLYLACTIC ACID-BASED RESIN MICROPARTICLES AND POLYLACTIC ACID-BASED RESIN MICROPARTICLES

摘要

A process of producing polylactic acid-based resin microparticles includes a dissolving step that forms a system, which can cause phase separation into two phases of a solution phase mainly composed of polylactic acid-based resin (A) having an enthalpy of fusion of less than 5 J/g and a solution phase mainly composed of polymer (B) different from polylactic acid-based resin, by dissolving the polylactic acid-based resin (A) and the polymer (B) different from polylactic acid-based resin in an ether-based organic solvent (C); an emulsion-forming step that forms an emulsion by applying a shear force to the system; and a microparticle-forming step that precipitates polylactic acid-based resin microparticles by contacting the emulsion with a poor solvent which has lower solubility of the polylactic acid-based resin (A) than the ether-based organic solvent (C).

主权项

1. A process of producing polylactic acid-based resin microparticles comprising:
a dissolving step that forms a system, which can cause phase separation into two phases of a solution phase mainly composed of polylactic acid-based resin (A) having an enthalpy of fusion of less than 5 J/g and a solution phase mainly composed of polymer (B) different from polylactic acid-based resin, by dissolving said polylactic acid-based resin (A) and said polymer (B) different from polylactic acid-based resin in an ether-based organic solvent (C); an emulsion-forming step that forms an emulsion by applying a shear force to said system; and a microparticle-forming step that precipitates polylactic acid-based resin microparticles by contacting said emulsion with a poor solvent which has lower solubility of said polylactic acid-based resin (A) than said ether-based organic solvent (C).