| 摘要 |
The invention at hand provides hydrolytically degradable ionic copolymers. These ionic copolymerizates are composed of one cyclic ketene acetal A, one anionic or cationic methacrylic acid derivative B, selected from 2-methyl-methacrylate, [2-(2-methyl-1-methylene-allyloxy)]ethanesulfonate, [2-(2-methyl-1-methylene-allyloxy)ethyl]phosphonate or a quaternary amine of the N,N-dimethylaminoethylmethacrylic acid (DMAEMA) and, optionally, a neutral methacrylic acid derivative C.;The hydrolytically degradable anionic copolymers according to the present invention are produced by polymerizing the components A, B and C in the presence of a radical initiator under inert gas atmosphere and subsequent purification.;All copolymers according to the present invention are hydrolytically degradable. Copolymers comprising a maximum of 40 mol-% of ester groups in the backbone are additionally biodegradable, wherein in the case of cationic copolymers a maximum of 20 mol-% of quaternized DMAEMA is allowed to be available.;Cationic copolymers comprising at least 50 mol-% of the component B are antimicrobial.;Both anionic as well as cationic copolymers are suitable for producing nanoparticles. Cationic copolymers are suitable for being used as superhydrophobic materials as well as adhesives. Anionic copolymers are suitable for biodegradable thermoplastic elastomers and for biodegradable ionomers. |
| 主权项 |
1. Hydrolytically degradable polyionic copolymerizates which are composed of
a) 10 to 55 mol-% of a cyclic ketene acetal A, b) 4 to 90 mol-% of a methacrylic acid derivative B, c) 0 to 80 mol-% of a methacrylic acid derivative C,wherein the sum of the components A, B and C results in 100 mol-% and wherein the cyclic ketene acetal A is selected fromwherein R1 and R2 stand independently of one another for a linear or branched alkyl group with 1 to 12 carbon atoms,and the methacrylic acid derivative B is selected from
N,N-dimethylaminoethylmethacrylic acid (DMEAMA) according to formula (Xa) wherein 45% to 95% of the DMEAMA are available ionized in the form of a quaternary amine of the formula (Xb), in such a way that the polyionic copolymerizate is a cationic copolymerizate, wherein R3 stands for a linear or branched alkyl group with 1 to 12 carbon atoms or a benzyl group of the formula (VII) where n=0-12 and X− stands for fluorine, chloride or bromide, and wherein the methacrylic acid derivative C is selected of compounds according to formula (VIII) wherein R4 is selected from —OCH3, —N(CH3)2, an oligoethylene glycol of the general formula —O—(CH2—CH2—O)mH, an ω-methoxy-oligoethylene glycol of the general formula —O—(CH2—CH2—O)m—CH3, wherein m represents a natural number between 1 and 12, vinyl acetate, acrylonitrile, 2-hydroxyethyl methacrylate, N-vinylformamide, N-vinylacetamide, N-methyl-N-vinylacetamide, N-vinylcaprolactame, N-vinylpyrrolidone, N-2-hydroxypropylmethacrylamide, N-3-hydroxpropylmethacrylamide, N,N-di methylacrylamide, styrene, N,N-dimethylaminostyrene. |
