发明名称 |
COMBINATION OF ANTI-CD20 ANTIBODY AND PI3 KINASE SELECTIVE INHIBITOR |
摘要 |
Highly effective combinations of a compound of formula A (a PI3Kδ selective inhibitor) and anti-CD20 antibodies are provided herein for the treatment and amelioration of PI3Kδ and/or CD20 mediated diseases and disorders. In particular, the combination can be used to treat cancers and autoimmune diseases. More particularly, the invention provided for a combination of a compound of formula A, or stereoisomers thereof, and ublituximab for the treatment and/or amerioration of hematological malignancies such as leukemia and lymphoma. |
申请公布号 |
SG11201503393S(A) |
申请公布日期 |
2015.06.29 |
申请号 |
SG11201503393S |
申请日期 |
2013.11.01 |
申请人 |
TG THERAPEUTICS, INC.;RHIZEN PHARMACEUTICALS SA;LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES |
发明人 |
WEISS, MICHAEL;MISKIN, HARI;SPORTELLI, PETER;VAKKALANKA, SWAROOP K.V.S. |
分类号 |
A61P35/00;A61K31/519;A61K39/395;A61K45/06;A61P37/00 |
主分类号 |
A61P35/00 |
代理机构 |
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地址 |
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