发明名称 METHOD FOR PRODUCING AND INDUCING TARGETED DIFFERENTIATION OF PULMONARY PLURIPOTENT CELL CULTURE
摘要 FIELD: medicine.SUBSTANCE: invention refers to biotechnology and medicine. What is presented is a method for differentiation of mesenchymal stem cells of fibrotic lungs into fibroblastic cells, characterised by recovering the cells self-maintaining in vitro for 60 days and having mesenchymal stem cell phenotype (CD44, CD73, CD90, CD106, CD31, CD34, CD45) from the right lobe of fibrotic lungs and producing the fibroblastic cells when adding fibroblast growth factor 2 mcg/ml to the mesenchymal stem cell culture.EFFECT: method enables producing the donor cells from the patients suffering idiopathic fibrosis from fibrotic pulmonary tissues.3 dwg, 1 ex
申请公布号 RU2554843(C2) 申请公布日期 2015.06.27
申请号 RU20130137272 申请日期 2013.08.08
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE NAUCHNOE UCHREZHDENIE "NAUCHNO-ISSLEDOVATEL'SKIJ INSTITUT FARMAKOLOGII I REGENERATIVNOJ MEDITSINY IMENI E.D.GOL'DBERGA" (NIIFIRM IM.E.D.GOL'DBERGA) 发明人 DYGAJ ALEKSANDR MIKHAJLOVICH;SKURIKHIN EVGENIJ GERMANOVICH;PERSHINA OL'GA VIKTOROVNA;KHMELEVSKAJA EKATERINA SERGEEVNA;KRUPIN VJACHESLAV ANDREEVICH;ERMAKOVA NATALIJA NIKOLAEVNA;REZTSOVA ALENA MIKHAJLOVNA
分类号 C12N5/02;C12N5/07 主分类号 C12N5/02
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