| 摘要 |
The invention belongs to the technical field of chemical catalysts, and in particular relates to a 2-aryl-zinc-propinoate catalyst and a preparation method and use thereof. The structural formula of the 2-aryl-zinc-propinoate catalyst of the present invention is one of the following. The catalyst can be used for homogeneous catalysis of a 1,2-aryl rearrangement reaction of alpha-haloaryl ketal, and especially for synthesizing non-steroid anti-inflammatory analgesic drugs of the 2-aryl propionic acid class with a high yield and which are environmentally friendly, for example ibuprofen, ketoprofen, loxoprofen, flurbiprofen, fenoprofen or naproxen and the like. |
