发明名称 |
ENGINEERED ALBUMIN BINDING POLYPEPTIDE |
摘要 |
The present disclosure relates to a class of engineered polypeptides having a binding affinity for albumin. In particular, the present invention relates to albumin binding polypeptides which have a high resistance to proteolytic cleavage and therapeutic use thereof. The disclosure provides an albumin binding polypeptide comprising an albumin binding motif, which motif consists of the amino acid sequence GXASDX5YKX8X9I X11X12AX14TVEGVX20 ALX23X24X25ILX28X29XB. |
申请公布号 |
WO2015091957(A1) |
申请公布日期 |
2015.06.25 |
申请号 |
WO2014EP78756 |
申请日期 |
2014.12.19 |
申请人 |
AFFIBODY AB |
发明人 |
EKBLAD, CAROLINE;FREJD, FREDRIK;LINDGREN, JOEL;ERIKSSON KARLSTRÖM,, AMELIE |
分类号 |
C07K14/76;A61K38/38 |
主分类号 |
C07K14/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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