发明名称 Therapeutic or preventive agent for diabetes
摘要 A collagen peptide mixture containing three or more kinds selected from Glu-Hyp-Gly, Glu-Hyp, Leu-Hyp-Gly, Pro-Ala, Ser-Hyp, Ala-Hyp-Gly, chemically-modified substances thereof and pharmaceutically acceptable salts thereof, and at least one peptide selected from the group consisting of Glu-Hyp-Gly, Glu-Hyp, Leu-Hyp-Gly, Pro-Ala, Ser-Hyp, Ala-Hyp-Gly, Pro-Hyp-Gly, Leu-Hyp, Ile-Hyp, Ser-Hyp-Gly, Gly-Pro-Hyp, (Pro-Hyp-Gly)5, Pro-Hyp, Hyp-Gly, Pro-Gly, Pro-Pro and Ala-Hyp or a chemically-modified substance thereof or a pharmaceutically acceptable salt thereof have DPPTV inhibitory activity and/or GLP-1 secretion accelerating activity, and hence are effective as a therapeutic or preventive agent or the like for diabetes.
申请公布号 US9061003(B2) 申请公布日期 2015.06.23
申请号 US201213981258 申请日期 2012.01.25
申请人 NITTA GELATIN INC. 发明人 Sugihara Fumihito;Inoue Naoki;Koizumi Seiko;Yoshimoto Tadashi;Oyama Hiroshi
分类号 A61K38/39;A61K38/05;A61K38/06;C07K5/062;C07K5/065;C07K5/072;C07K5/083;C07K5/087;C07K5/093;C07K5/097 主分类号 A61K38/39
代理机构 Lathrop & Gage LLP 代理人 Lathrop & Gage LLP ;Velema, Esq. James H.
主权项 1. A method for treatment of diabetes comprising administering the dipeptide Pro-Ala or a pharmaceutically acceptable salt thereof to a subject in need thereof.
地址 Osaka JP