发明名称 PHOSPHORAMIDATE DERIVATIVES OF NUCLEOSIDES
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: invention relates to compounds intended for treatment of hepatitis C of formula:its stereoisomeric forms, pharmaceutically acceptable salts or solvates, where Rrepresents hydrogen; Rrepresents hydrogen, napthyl or phenyl, optionally substituted with 1, 2 or 3 substituents, selected from halogen and C-Calkyl; Rand Rrepresent hydrogen or C-Calkyl; Rrepresents C-Calkyl, optionally substituted with C-Calkoxygroup, C-Ccycloalkyl or benzyl; Rrepresents hydrogen.EFFECT: claimed are novel compounds and composition on their base, effective against hepatitis C.12 cl, 4 ex, 1 tbl
申请公布号 RU2553656(C2) 申请公布日期 2015.06.20
申请号 RU20120117829 申请日期 2010.09.29
申请人 JANSSEN PRODAKTS, EHL.PI.;MEDIVIR AB 发明人 JONKERS TIM KH'JUGO MARIJA;RABUASSON P'ER ZHAN-MARI BERNAR;VANDIK KOEHN;PEL'KMAN MIKAEHL';SUND BENGT KRIST'JAN;VEKHLING KHORST JURGEN;PASUSH PIN'JU PEDRO MANUEHL;VINKVIST ANNA;NIL'SSON KARL MAGNUS
分类号 C07H19/10;A61K31/7072;A61P31/14 主分类号 C07H19/10
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