Lp(a) SUBFORM SIZE IDENTIFICATION USING ZONAL GEL IMMUNO-FIXATION ELECTROPHORESIS

摘要

In one aspect, a method for determining the composition of individual Lp(a) subforms in a test sample is provided. The method involves providing a test sample comprising Lp(a) subforms obtained from a subject; separating the Lp(a) subforms in the test sample along an electrophoretic gel; measuring the migration velocity of the individual Lp(a) subforms along the electrophoretic gel; comparing, based on said measuring, the migration velocity of the individual Lp(a) subforms to a reference value; and determining, based on said comparing, the molar mass of the individual Lp(a) subforms. Methods for predicting cardiovascular health are also provided.

主权项

1. A method for determining the composition of individual Lp(a) subforms in a test sample, the method comprising:
(a) providing a test sample comprising Lp(a) subforms obtained from a subject; (b) separating the Lp(a) subforms in the test sample along an electrophoretic gel; (c) measuring the migration velocity of the individual Lp(a) subforms along the electrophoretic gel; (d) comparing, based on said measuring, the migration velocity of the individual Lp(a) subforms to a reference value; and (e) determining, based on said comparing, the molar mass of the individual Lp(a) subforms.