发明名称 |
TETRAHYDROBENZIMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY |
摘要 |
A series of substituted 4,5,6,7-tetrahydrobenzimidazole derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders. |
申请公布号 |
WO2015086513(A1) |
申请公布日期 |
2015.06.18 |
申请号 |
WO2014EP76854 |
申请日期 |
2014.12.08 |
申请人 |
UCB BIOPHARMA SPRL |
发明人 |
HEER, JAG PAUL;JACKSON, VICTORIA ELIZABETH;KROEPLIEN, BORIS;LECOMTE, FABIEN CLAUDE;PORTER, JOHN ROBERT |
分类号 |
C07D235/12;A61K31/4184;A61P29/00 |
主分类号 |
C07D235/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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