摘要 |
<p>The present invention provides a process comprising reacting a halogenated thiocarbonyl compound represented by Formula (1):
wherein Ar is an optionally substituted aryl group and X is a halogen atom, with an Grignard compound represented by Formula (2): R-MgY wherein R is an optionally substituted aryl group or an optionally substituted cycloalkyl group and Y is a halogen atom. This process can produce the desired arylthionocarboxylic acid ester represented by Formula (3):
wherein Ar and R are as defined above, in a high yield under relatively mild reaction conditions.</p> |